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Denigma
»
Lifespan
»
Variants
» Variant = rs1801274
o
|
Admin
Mouse Lifespan Experiments
(
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)
rs1801274
Polymorphism:
rs1801274
rs1801274
(
SNPedia
|
23andMe
)
Variant Type:
SNP
Location:
1q23
Factor:
- Symbol:
FCGR2A
- Name:
Fc fragment of IgG, low affinity IIa, receptor (CD32)
- Entrez ID:
2212
- Ensembl ID:
ENSG00000143226
Factors:
FCGR2A
Fc fragment of IgG, low affinity IIa, receptor (CD32)
(
2212
/
ENSG00000143226
)
Description:
Three age groups (adult, elderly and centenarian)
Ethnicity:
German
Age of cases:
100–110/ mean101.3
Shorter lived allele:
(SNP is His/Arg)
Finding:
Negative
Statistics
- Number of cases/controls:
408 vs 446 vs 454 (initial)
- p-value:
0.05 [> 0.05]
- Significant:
No
Study Design
- Classifications:
No Age Effect
- Study type:
Candidate Region/Gene
Reference:
16893392: The FCGR2A--Arg131 variant is no major mortality factor in the elderly--evidence from a German centenarian study.
Choice:
Curate
Created:
July 2, 2013, 2:47 a.m.
Updated:
Aug. 8, 2014, 1:06 p.m.
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