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Denigma
»
Lifespan
»
Variants
» Variant = rs572169
o
|
Admin
Mouse Lifespan Experiments
(
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)
rs572169
Polymorphism:
rs572169
rs572169
(
SNPedia
|
23andMe
)
Variant Type:
SNP
Location:
3q26.31
Factor:
- Symbol:
GHSR
- Name:
growth hormone secretagogue receptor
- Entrez ID:
2693
- Ensembl ID:
ENSG00000121853
Factors:
GHSR
growth hormone secretagogue receptor
(
2693
/
ENSG00000121853
)
Ethnicity:
Danish
Age of cases:
92-93 years old
Shorter lived allele:
A
Longer lived allele:
G
Finding:
Positive
Statistics
- Number of cases/controls:
1089 vs 736 (initial)
|
1613 vs 1104 (replication)
- Odds ratio:
0.725
- p-value:
0.0045 [0.0045]
- Significant:
Yes
Study Design
- Classifications:
Longevity-Associated
- Study type:
Candidate Region/Gene
- Technology:
Illumina GoldenGate platform
Reference:
22406557: Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies.
Choice:
Curate_Emily
Created:
July 1, 2013, 10:43 a.m.
Updated:
Aug. 8, 2014, 1:05 p.m.
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