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Denigma
»
Lifespan
»
Variants
» Variant = rs2267723
o
|
Admin
Mouse Lifespan Experiments
(
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)
rs2267723
Polymorphism:
rs2267723
rs2267723
(
SNPedia
|
23andMe
)
Variant Type:
SNP
Location:
7p14
Factor:
- Symbol:
GHRHR
- Name:
growth hormone releasing hormone receptor
- Entrez ID:
2692
- Ensembl ID:
ENSG00000106128
Factors:
GHRHR
growth hormone releasing hormone receptor
(
2692
/
ENSG00000106128
)
Ethnicity:
Danish
Age of cases:
92.2–93.8 (mean age 93.2)
Shorter lived allele:
G
Finding:
Positive
Statistics
- Number of cases/controls:
1089 vs 736 (initial)
|
1613 vs 1104 (replication)
- Odds ratio:
0.696
- p-value:
0.0001 [0.0001]
- Significant:
Yes
Study Design
- Classifications:
Longevity-Associated
- Study type:
Candidate Region/Gene
Reference:
22406557: Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies.
Choice:
Curate
Created:
July 2, 2013, 2:48 a.m.
Updated:
Aug. 8, 2014, 1:06 p.m.
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