Symbol: URE2 Name: UREidosuccinate transport 2 Entrez gene ID: 855492 Ensembl gene ID: YNL229C Species: Yeast (Taxid: 4932) Functional description: Ure2p; Nitrogen catabolite repression transcriptional regulator that acts by inhibition of GLN3 transcription in good nitrogen source; has glutathione peroxidase activity and can mutate to acquire GST activity; altered form creates [URE3] prion [Source:SGD;Acc:S000005173] [Ensembl] Observation: Deletion of URE2 increase mean replicative lifespan by 21-31% in BY4742 [16293764]. URE2 deletion increases replicative lifespan increased by 20% in the alpha strain [19030232]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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