Symbol: SdhB Name: Succinate dehydrogenase B Entrez gene ID: 35590 Ensembl gene ID: FBgn0014028 Species: Fly (Taxid: 7227) Functional description: Succinate dehydrogenase B; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). [UniProt] Observation: SdhB mutants are hypersensitive to oxygen and displays signs of premature aging, including a 66% decrease in mean lifespan and a 17% decrease in maximum lifespan [17056719]. Interventions: Assays: Organismal Lifespan Mean: -66 Maximum: -17 Classification: References: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
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