Denigma

prdx-3

Symbol: prdx-3
Name: PeRoxireDoXin
Entrez gene ID: 175573
Ensembl gene ID: R07E5.2
Species: Worm (Taxid: 6239)

Functional description:
Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity). [UniProt]

Observation:

RNA interference resulted in decreased lifespan and earlier accumulation of lipofuscin.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • PRDX3 (9606)
  • LOC465865 (9598)
  • LOC477839 (9615)
  • LOC611135 (9615)
  • LOC608154 (9615)
  • PRDX3 (9913)
  • Prdx3 (10090)
  • Prdx3 (10116)
  • PRDX3 (9031)
  • prdx3 (7955)
  • Prx5037 (7227)
  • TPX1 (7165)
  • prdx-3 (6239)



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