Symbol: lsd-1 Name: Lysine-Specific histone Demethylase homolog Entrez gene ID: 181369 Ensembl gene ID: T08D10.2 Species: Worm (Taxid: 6239) Functional description: Protein LSD-1; Lysine-Specific histone Demethylase homolog family member (lsd-1) [Source:RefSeq peptide;Acc:NP_510000] [Ensembl]; T08D10.2 encodes an ortholog of the human histone demethylase LSD1 (KIAA0601), and a paralog of C. elegans SPR-5; similar histone demethylase homologs are found in human, mouse, Drosophila, fission yeast, and Arabidopsis; T08D10.2 is predicted to demethylate histone H3 lysine 4 residues and act as a transcriptional corepressor. [WormBase] Observation: T08D10.2 RNAi is extend median longevity by 28% [17959600]. Assays: Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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