Polymorphism: APOE haplotype - rs1346044
rs1346044
(
SNPedia |
23andMe
)
Variant Type: Haplotype
Location: 19q13.2
Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203
Factors:
APOE
apolipoprotein E
(
348
/
ENSG00000130203
)
Description:
There was no significant association between rs1346044 and longevity, but it was between APOE haplotype and longevity.
Ethnicity:
Finn
Age of cases: 100.8
Shorter lived allele: e4
Longer lived allele: e2
Finding: Positive
Statistics
- Number of cases/controls: 175 vs 178 (initial)
- p-value:
0.0001
[<0.0001]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR
Reference:
10069711: Polymorphisms at the Werner locus: I. Newly identified polymorphisms, ethnic variability of 1367Cys/Arg, and its stability in a population of Finnish centenarians.
Choice: Clean
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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