Polymorphism: rs11640851
rs11640851
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 16q13
Factor:
- Symbol: MT1a
- Name: metallothionein 1A
- Entrez ID: 4489
- Ensembl ID: ENSG00000205362
Factors:
MT1a
metallothionein 1A
(
4489
/
ENSG00000205362
)
Description:
Applies only to females. "... this polymorphism might not be associated to the longevity in old female." rs8052394 was in tight LD with rs11640851. Significant haplotype frequency difference between controls and cases was found. MT1a Arg/Asp haplotype increased in cases; MT1a Lys/Thr haplotype decreased in cases: Haplotype (Arg/Asp) might be favourable for the longevity
Ethnicity:
Italian
Age of cases: Mean age 91.4 +/- 4.1
Statistics
- Number of cases/controls: 151 vs 100 (initial)
- p-value:
[>0.05]
- Significant: No
Study Design
- Classifications:
No Age Effect
- Study type: Candidate Region/Gene
- Technology: PCR based method
Reference:
16955215: Polymorphisms in MT1a gene coding region are associated with longevity in Italian Central female population.
Choice: Clean
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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