Denigma Buck Institute Health Extension
Polymorphism: rs1137100
rs1137100 ( SNPedia | 23andMe )

Variant Type: SNP

Factor:
- Symbol: LEPR
- Name: leptin receptor
- Entrez ID: 3953
- Ensembl ID: ENSG00000116678

Factors:
  • LEPR leptin receptor ( 3953 / ENSG00000116678 )

    • Ethnicity: Polish
    Age of cases: 100+
    Shorter lived allele: AA
    Finding: Positive

    Statistics
    - Number of cases/controls: 128 vs 414 (initial)
    - Odds ratio type:
    - p-value: 0.026 [0.026]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology:

    Reference:
    24549597: Functional polymorphisms of the leptin and leptin receptor genes are associated with longevity and with the risk of myocardial infarction and of type 2 diabetes mellitus.

    Choice: Curate
    Created: Aug. 31, 2014, 9:35 p.m.
    Updated: Aug. 31, 2014, 9:35 p.m.

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