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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs915179-rs2485662-rs4641-rs1468772 | LMNA | 1.56 | 2.5e-05 | 873 vs 443 | New England Centenarian Study (NECS) (N = 738), (ii) the Southern Italian Centenarian Study (SICS) (N = 905), (iii) France (N = 1103), and (iv) the Einstein Ashkenazi Longevity Study (N = 702) | American, Caucasian | Mean age 101.5 | — | GTCT | Candidate Region/Gene | 22340368 |
| rs1544410-rs17878969 | VDR | 15.30 | 0.001 | 104 vs 114 | — | Caucasian, Spaniard | >85 | non G-S haplotypes | G-S | Candidate Region/Gene | 20407924 |
| rs11568820-rs4516035-rs10735810-rs1544410-rs17878969 | VDR | 11.50 | 0.024 | 104 vs 114 | — | Caucasian, Spaniard | >85 | G-G-C-G-S | non G-G-C-G-S haplotypes | Candidate Region/Gene | 20407924 |