| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs1042718-rs1042719 | ADRB2 | 0.63 | 1.86e-05 | 384 vs 384 | 579 vs 644 | Chinese | Mean age 102.1±0.20 | G-C | A-C | Candidate Region/Gene | 23020224 |
| rs915179-rs2485662-rs4641-rs1468772 | LMNA | 1.56 | 2.5e-05 | 873 vs 443 | New England Centenarian Study (NECS) (N = 738), (ii) the Southern Italian Centenarian Study (SICS) (N = 905), (iii) France (N = 1103), and (iv) the Einstein Ashkenazi Longevity Study (N = 702) | American, Caucasian | Mean age 101.5 | — | GTCT | Candidate Region/Gene | 22340368 |
| APOE polymorphism | APOE | — | 0.0001 | 291 vs 589 | — | Finn | Mean age 97.5 | e4 | e2 | Candidate Region/Gene | 16487435 |
| APOE haplotype - rs1346044 | APOE | — | 0.0001 | 175 vs 178 | — | Finn | 100.8 | e4 | e2 | Candidate Region/Gene | 10069711 |
| mtDNA haplogroups | mtDNA | 0.40 | 0.0003 | 74 vs 187 | — | Amish | >80 years | J | non-J | Mitochondrial Haplogroup | 21750925 |
| APOE polymorphism | APOE | 3.26 | 0.001 | 64 vs 1344 | — | Italian | 100+ | e4 | e2 | Candidate Region/Gene | 16960022 |
| rs11279109 - APOB XbaI | APOB | — | 0.001 | 191 (case) vs 53 (initial) | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | — | D - X+ | Candidate Region/Gene | 17393087 |
| rs1544410-rs17878969 | VDR | 15.30 | 0.001 | 104 vs 114 | — | Caucasian, Spaniard | >85 | non G-S haplotypes | G-S | Candidate Region/Gene | 20407924 |
| rs429358, rs7412 | APOE | — | 0.001 | 179 vs 615 | — | Finn | Mean age 100 | e4 | e2, e3 | Candidate Region/Gene | 8018664 |
| e4 | APOE | 0.35 | 0.001 | 729 vs 498 | — | Japanese | 100+ | e4 | — | Candidate Region/Gene | 24534555 |
| mtDNA haplogroups | mtDNA | 7.56 | 0.0015 | 74 vs 187 | — | Amish | >80 years | non-X | X | Mitochondrial Haplogroup | 21750925 |
| APOE polymorphism | APOE | 0.38 | 0.002 | 200 (cases) vs 539 | — | Italian | >88 | e4 | e2 | Candidate Region/Gene | 21703254 |
| rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581 | CDKN1A | — | 0.00211 | 184 vs 184 | — | Italian | 100 | non G-G-G-C-C-G haplotypes | G-G-G-C-C-G | Candidate Region/Gene | 20126416 |
| rs3176343-rs3176344-rs3176349-rs1801270 | CDKN1A | — | 0.00394 | 184 vs 184 | — | Italian | 100 | non G-G-G-C haplotypes | G-G-G-C | Candidate Region/Gene | 20126416 |
| REN polymorphism - mtDNA | mtDNA | 3.27 | 0.006 | 157 | — | Italian | 100+ | — | REN10 - mtDNA haplogroup H | Candidate Region/Gene | 11938442 |
| APOB XbaI − SI000565Q | APOB | — | 0.006 | 191 (case) vs 53 (initial) | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | X+ - Short | X+ - Medium | Candidate Region/Gene | 17393087 |
| apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90+ | apoE4 | — | Candidate Region/Gene | 11780357 |
| apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90 | apoE4 | ApT4 | Candidate Region/Gene | 11780357 |
| apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90 | apoE4 | — | Candidate Region/Gene | 11780357 |
| APOE polymorphism - HP1/2 common polymorphism | APOE | — | 0.013 | 200 (cases) vs 539 (initial) | — | Italian | >88 | e4-H2 (haplotype) | — | Candidate Region/Gene | 21703254 |
| A-3826G (rs1800592) - C-3740A | UCP1 | 0.81 | 0.014 | 236 vs 741 | — | Italian | >91 | G-A | — | Candidate Region/Gene | 21827845 |
| rs1061581 - rs1008438 - rs2227956 | Hsp70Ba | 0.55 | 0.015 | 168 cases | — | Danish | Mean age 92.8 +/- 0.4 | — | G-C-T (haplotype) | Candidate Region/Gene | 20388090 |
| rs1061581-rs1043618-rs2227956 | — | 4.51 | 0.016 | 191 vs 53 | — | Chinese | >90 | non A-G-C or non A-C-T haplotypes | A-C-T | Candidate Region/Gene | 19840767 |
| 5417A,10873T | mtDNA | — | 0.018 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| HP 1/2 | HP | 1.27 | 0.0194 | 1072 total | — | Italian | >88 | HP*2 | HP*1 | Candidate Region/Gene | 21147083 |
