| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs1801133 | MTHFR | — | 0.06 | 564 vs. 374 | — | French | mean age 100.71 | TT | CT, CC | Candidate Region/Gene | 9106548 |
| rs662 | PON1 | 1.06 | 0.11 | — | — | Danish, Dutch, French, German, Italian, Tatar | >/=80 | — | — | Candidate Region/Gene | 20362697 |
| - | SIRT3 | — | 0.145 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| I/D (insertion/deletion) | ACE | — | 0.33 | 560 vs 560 | — | French | centenarians 100th year or beyond, mean age 103.1 | — | — | Candidate Region/Gene | 11280044 |
| CYP2D6*3 | CYP2D6 | — | 1.0 | 552 vs 243 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| CYP2D6*4 | CYP2D6 | — | 1.0 | 523 vs 252 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| GSTM1 deletion | GSTM1 | — | 1.0 | 565 vs 229 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| NAT2*5A (C 481 T), NAT2*6A (G 590 A), NAT2*7A (G 857 A), and NAT2*14A (G 191 A) | NAT2 | — | 1.0 | 188 vs 88 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| - | PARP1 | — | 1.0 | 239 vs 198 | — | French | >100 | — | — | Candidate Region/Gene | 9587069 |
