"We found that familial longevity was associated with... a lower frequency of allelic variation in the CYP2R1 gene [rs2060793]." Also, may include not healthy individuals ("There was no selection based on health conditions or demographic characteristics.")
Ethnicity:Dutch Age of cases: Males: >/= 89; Females: >/= 91
Statistics - Number of cases/controls: 1038 (offspring of nonagenarians who had at least one nonagenarian sibling) vs 461 (offsprings' partners) (initial)
- p-value:
0.04
[0.04]
- Significant: Yes
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