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Denigma
»
Lifespan
»
Variants
» Variant = rs1800896
o
|
Admin
Mouse Lifespan Experiments
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rs1800896
Polymorphism:
rs1800896
rs1800896
(
SNPedia
|
23andMe
)
Variant Type:
SNP
Location:
1q31-q32
Factor:
- Symbol:
IL10
- Name:
interleukin 10
- Entrez ID:
3586
- Ensembl ID:
ENSG00000136634
Factors:
IL10
interleukin 10
(
3586
/
ENSG00000136634
)
Description:
Only significant in men Trivial name is -1082G/A
Ethnicity:
Italian
Age of cases:
>100
Longer lived allele:
GG
Finding:
Positive
Statistics
- Number of cases/controls:
174 vs 227 (initial)
- p-value:
0.019 [0.019 (only in males)]
- Significant:
Yes
Study Design
- Classifications:
Longevity-Associated
- Study type:
Candidate Region/Gene
- Technology:
PCR
Reference:
12676903: Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 -1082 promoter SNP and its interaction with TNF-alpha -308 promoter SNP.
Choice:
Clean
Created:
July 1, 2013, 10:42 a.m.
Updated:
Aug. 8, 2014, 1:05 p.m.
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