(rs429358, rs7412) + (rs2075650)

Polymorphism: (rs429358, rs7412) + (rs2075650)
(rs429358, ( SNPedia | 23andMe )
rs7412) ( SNPedia | 23andMe )

(rs2075650) ( SNPedia | 23andMe )


Factor:
- Symbol: APOE + TOMM40

Factors:

APOE + TOMM40

Description:

Not significant because the linkage disequilibrium was weak.

Ethnicity: Dutch
Age of cases: Mean age 94
Shorter lived allele: e4 + G
Finding: Negative

Statistics
- Number of cases/controls: 403 vs 1670 (initial) | 3746 vs 5912 (replication)
- Odds ratio: 0.93
- p-value: 0.337 [0.337]
- Significant: No

Study Design
- Classifications: No Age Effect
- Study type: Genome-Wide Association Study
- Technology: Illumina Infinium HD Human660W-Quad BeadChips; Illumina Infinium II HumanHap550-Duo BeadChips

Reference:
21418511: Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.

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