Interventions

  • Species: + -
  • name effect species mean median maximum
    ndc-80 RNAi ndc-80 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    lys-1 RNAi lys-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    let-92 RNAi let-92 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    his-2 RNAi his-2 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    gsk-3 RNAi gsk-3 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    pcf-11 RNAi pcf-11 RNAi in the adulthood decreases mean and maximum lifespan by 19 and 25% [23144747]. Worm -18.9 -25.0
    snap-1 RNAi snap-1 RNAi in the adulthood reduces mean and maximum lifespan by 40 and 50%, respectively [23144747]. Worm -39.9 -50.0
    dcn-1 RNAi dcn-1 RNAi in the adulthood extends the lifespan [23144747]. Worm
    F16D3.4 RNAi F16D3.4 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    rps-12 RNAi rps-12 RNAi in the adulthood extends mean and maximum lifespan by 12 and 22%, respectively [23144747]. Worm +11.6 +21.7
    rpa-1 RNAi rpa-1 RNAi in the adulthood extends the mean and maximum lifespan by 5 and 22%, respectively [23144747]. Worm +5.1 +21.7
    asb-1 RNAi asb-1 RNAi in the adulthood extends the mean lifespan by 7% without changing the maximum lifespan [23144747]. Worm +6.4 0
    eif-3.E RNAi eif-3.E RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    rsp-8 RNAi rsp-8 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    T23D8.3 RNAi T23D8.3 RNAi in the adulthood extends mean and maximum lifespan by 26% and 35, respectively [23144747]. Worm +25.7 +34.7
    F09F7.3 RNAi F09F7.3 RNAi in the adulthood extends mean and maximum lifespan by 8 and 22%, respectively [23144747]. Worm +8.1 +21.7
    rpb-8 RNAi rpb-8 RNAi in the adulthood extends the mean lifespan by 6% without any apparent effect on maximum lifespan [23144747]. Worm +6.4 0
    chn-1 RNAi chn-1 RNAi in the adulthood extends mean and maximum lifespan by 7 and 9%, respectively [23144747]. Worm +7.1 +8.7
    fkb-6 RNAi fkb-6 RNAi in the adulthood extends the mean lifespan by 2.9% [New longevity regulators]. Worm +2.4
    gpd-3 RNAi gpd-3 RNAi in the adulthood extends the mean lifespan by 5% without a change in maximum lifespan [23144747]. Worm +5.3 0
    nhr-23 RNAi nhr-23 RNAi in the adulthood extends mean and maximum lifespan by 5 and 9%, respectively [23144747]. Worm +4.9 +8.7
    rsr-1 RNAi rsr-1 RNAi in the adulthood extends the mean lifespan by 6% without an effect on maximum lifespan [23144747]. Worm +6.1 0
    B0393.6 RNAi B0393.6 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    T04A8.11 RNAi T04A8.11 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    F09F7.4 RNAi F09F7.4 RNAi in the adulthood extends the lifespan [New longevity regulators]. RNAi against F09F7.4 started after the animal reached the late L4 stage increases mean lifespan by 6-12% [22103665]. Worm +6 to +12
    Interventions are an extension of GenAge and GenDR.