Denigma

Interventions

  • Species: + -
    House mouse « 
  • Manipulation: + -
    Gain‑of‑Function «  Overexpression «  Mutation (1)   Deletion (1)   Gene Therapy (1)  
    • name effect species mean median maximum
    Sirt6 overexpression Overexpression of Sirt6 in male mice lengthens the median lifespan by 9.9-14.5% and maximum lifespan by 13.1-15.8% [22367546]. Mouse — +9.9 to +14.5 +13.1 to +15.8
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    • 1 of 26 interventions
    Interventions are an extension of GenAge and GenDR.