aPKC transposition | Insertion of a P-based vectors in the structural part of aPKC increase male and female lifespan [22661237]. | Fly | — | — | — |
esg transposition | Disruption of esg by insertion of the P{GT1} vector 300 bp downstream of its structural part increases male and female lifespan [22661237]. | Fly | — | — | — |
CYR1 transposition | Transposon-mutagenized CYR1 increases resistance to oxidants and extends chronological lifespan by up to 90%. Stress-resistance transcription factors Msn2/Msn4 and protein kinase Rim15 are required for this lifespan extension [11292860]. | Yeast | +300 | — | — |
SCH9 Transposition | Transposon-mediated mutagenesis of SCH9, which encodes for a serine threonine kinase homologous to Akt/PKB, increases resistance to oxidants and thermal stress as well as extends chronological lifespan by 30% [11292860]. | Yeast | +30 | — | — |
insc transposition | insc disruption through an insertion of the P{EPgy2} vector in ts structural part prolongs female lifespan [22661237]. | Fly | — | — | — |
Hsp22 transposition | Animals that do not express Hsp22 (due to a transposition into its transcriptional starting site) have a 40% decrease in lifespan, exhibit a 30% decrease in locomotor activity and are sensitive to mild stress [20036725]. | Fly | -40 | — | — |