Denigma

Interventions

  • Species: + -
    House mouse « 
  • Manipulation: + -
    Deletion «  Gain‑of‑Function (1)   Loss‑of‑Function (25)   Knockout (21)   Overexpression (1)   Mutation (25)  
    • name effect species mean median maximum
    Top3b knockout Homozygous disruption of Top3b results in a normal development but a shorter lifespan (by approximately 70%) accompanied by lesions in multiple organs in C57BL/6 [11331780]. Mouse -70 — —
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    • 1 of 26 interventions
    Interventions are an extension of GenAge and GenDR.