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Ontology of Gerontology
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Interventions
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Species:
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Human «
Manipulation:
+
-
Loss‑of‑Function «
Deletion «
Mutation (1)
name
effect
species
mean
median
maximum
Homozygous GH1 deletion
Mean lifespan in untreated, affected individuals homozyogus for a deletion at the GH1 locus is significantly shorter (P < 0.05) than in affected siblings or the general population. Individuals homozygous for GH1 deletion demonstrate hereditary dwarfism [
12915652
].
Human
—
—
—
1 intervention
Interventions are an extension of
GenAge
and
GenDR
.