Interventions

  • Species: + -
  • name effect species mean median maximum
    zyg-11 RNAi zyg-11 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    ZC395.10 RNAi ZC395.10 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    Y41E3.11 RNAi Y41E3.11 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    xrn-1 RNAi xrn-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    wah-1 RNAi wah-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. RNAi against wah-1 started after the animal reaches the late L4 stage extends mean lifespan by 7-8% [22103665]. Worm +7 to +8
    vit-2 RNAi vit-2 RNA interference extends mean lifespan by 21-24% [12845331]. Worm +21 to +24
    vit-1 RNAi vit-1 RNAi animals have a mean lifespan that 103.3% of controls, but not significant different [12845331]. Worm
    vig-1 RNAi vig-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    vab-1 RNAi vab-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    trap-4 RNAi trap-4 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    tba-5 RNAi tba-5 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    tag-341 RNAi tag-341 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    tag-322 RNAi tag-322 RNAi increases mean and maximum lifespan by 18 and 12%, respectively [19293945]. Worm +18 +12
    T23D8.3 RNAi T23D8.3 RNAi in the adulthood extends mean and maximum lifespan by 26% and 35, respectively [23144747]. Worm +25.7 +34.7
    T08A11.2 RNAi T08A11.2 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    T04A8.11 RNAi T04A8.11 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    synaptobrevin RNAi synaptobrevin RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    sur-2 RNAi sur-2 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    srh-20 RNAi srh-20 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    sos-1 RNAi sos-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    snr-5 RNAi snr-5 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
    snap-1 RNAi snap-1 RNAi in the adulthood reduces mean and maximum lifespan by 40 and 50%, respectively [23144747]. Worm -39.9 -50.0
    slcf-1 RNAi slcf-1 RNAi extends the lifespan [21040400]. Worm
    scl-20 RNAi scl-20 appears to inhibit the growth of gld-1 tumours. RNA interference of scl-20 reduces mean lifespan up to 18% in wild-type animals, 15% in daf-2 mutants and 28% in daf-2/gld-1 mutants [17934462]. Worm -18
    sbp-1 RNAi sbp-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. Worm
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    • 25 of 528 interventions
    Interventions are an extension of GenAge and GenDR.