CG12004 | — | CG12004 exhibits a coding region difference unique to animals under experimental evolution selected for longevity and is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
CG12090 | — | CG12090 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
CG7852 | — | CG7852 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and is differentially expressed in head and abdomen of animals that were selected for longevity [23106705]. | Fruit fly |
CG13917 | — | CG13917 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
CG12016 | — | CG12016 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
kst | karst | kst exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it has three differentially expressed transcripts in head of animals that were selected for longevity [23106705]. | Fruit fly |
LanB2 | Laminin B2 | LanB2 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
CG16711 | — | CG16711 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
Doc1 | — | Doc1 exhibits a coding region difference unique to animals under experimental evolution selected for longevity and is differentially expressed in the abdomen of for longevity selected lines [23106705].
| Fruit fly |
CG4942 | — | CG4942 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
CG32022 | — | CG32022 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
CG12576 | — | CG12576 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
Rh2 | Rhodopsin 2 | Rh2 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
endoA | endophilin A | endoA exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
CG6184 | — | CG6184 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
CG6195 | — | CG6195 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it is differentially expressed in abdomen of animals that were selected for longevity [23106705]. | Fruit fly |
CG16718 | — | CG16718 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it is differentially expressed in abdomen of animals that were selected for longevity [23106705]. | Fruit fly |
fry | furry | fry exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it is differentially expressed in abdomen of animals that were selected for longevity [23106705]. | Fruit fly |
CG34243 | — | CG34243 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and it is differentially expressed in head of animals that were selected for longevity [23106705]. | Fruit fly |
Cct1 | CTP:phosphocholine cytidylyltransferase 1 | Overexpression of Cct1 from a doxycycline-inducible promoter results in a 6 - 8% increase in mean lifespan (in the PdL x rtTA; Oregon-R x rtTA strain) [12620118].
Cct1 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and is upregulated in head of animals that were selected for longevity at all ages beyond the day of eclosion [23106705]. | Fruit fly |
Psa | Puromycin sensitive aminopeptidase | Psa exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and is upregulated in head of animals that were selected for longevity at all ages except 50 days [23106705]. Experimental u-regulation of Psa protects against tau-induced neurodegeneration [16950154]. | Fruit fly |
dro2 | drosomycin-2 | dro2 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and is downregulated in head of animals that were selected for longevity at early and intermediate ages [23106705]. | Fruit fly |
dro4 | drosomycin-4 | dro4 exhibits a non-coding region difference unique to animals under experimental evolution selected for longevity and is downregulated in head of animals that were selected for longevity at early and intermediate ages [23106705]. | Fruit fly |
MIR21 | MIRN21; hsa-mir-21; miR-21; miRNA21 | MIR21 is the most highly expressed microRNA gene in octogenarians and centenarians. MIR21 expression is higher under cardiovascular diseases and lower in centenarian offspring. MIR21 is correlated with C-reactive protein and fibrinogen levels. TGF-βR2 mRNA, a MIR21 target, exhibits the highest expression in leukocytes form a subset of octogenarians. MIR-21 may be a biomarker of inflammation [23041385]. | Human |
— | — | ENSRNOG00000044316 is transcriptional downregulated in the cerebral cortex at the age 28 months under different longevity conditions such as under dietary restriction (DR) as well as in feeding switch regimens that result in extended lifespan, like early age switch to DR as well as the reverse switch under the influence of the DR-mimetic α-lipoic acid (i.e. DR switched to ad libitum+ lipoic acid) [Shona et al. 2013]. | Norway rat |