Denigma

IDP2

Symbol: IDP2
Name: Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose
Entrez gene ID: 850871
Species: Yeast (Taxid: 4932)

Functional description:
Idp2p; Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose [Source:SGD;Acc:S000004164] [Ensembl]

Observation:

Replicative lifespan increased by 25% in the alpha strain and decreased by 10% in the a strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • IDH2 (9606)
  • IDH2 (9598)
  • IDH2 (9615)
  • IDH2 (9913)
  • Idh2 (10090)
  • Idh2 (10116)
  • idh2 (7955)
  • AgaP_AGAP003168 (7165)
  • C34F6.8 (6239)
  • IDP2 (4932)
  • KLLA0F12342g (28985)
  • AGOS_AAL022W (33169)
  • ICDH (3702)
  • Os01g0248400 (4530)



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