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Symbol: ESC2 Name: Protein involved in mating-type locus silencing, interacts with Sir2p; probably functions to recruit or stabilize Sir proteins Entrez gene ID: 851965 Species: Yeast (Taxid: 4932) Functional description: Esc2p; Sumo-like domain protein; prevents accumulation of toxic intermediates during replication-associated recombinational repair; roles in silencing, lifespan, chromatid cohesion and the intra-S-phase DNA damage checkpoint; RENi family member [Source:SGD;Acc:S000002771] [Ensembl] Observation: Replicative lifespan decreased by 50% in the alpha strain Assays: Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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