Symbol: UTH1 Name: yoUTH 1 Entrez gene ID: 853916 Ensembl gene ID: YKR042W Species: Yeast (Taxid: 4932) Functional description: Uth1p; Mitochondrial outer membrane and cell wall localized SUN family member involved in cell wall biogenesis and required for mitochondrial autophagy; involved in the oxidative stress response, life span during starvation, and cell death [Source:SGD;Acc:S000001750] [Ensembl] Observation: Mutation in UTH1 increases replicative lifespan by approximately 15% [7859289]. UTH1 mutant has enhanced stress resistance to cold stress [7859289], heat shock [10870102], starvation [7859289], hydrogen peroxide, but is sensitive to paraquat and oxygen [9799359]. Interventions: Assays: Replicative Lifespan Classification: References: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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