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Symbol: Scgdelta Name: Sarcoglycan delta Entrez gene ID: 31129 Ensembl gene ID: FBgn0025391 Species: Fly (Taxid: 7227) Functional description: Forms a link between the F-actin cytoskeleton and the extracellular matrix; Sarcoglycan delta; Sarcoglycan delta [Source:FlyBase gene name;Acc:FBgn0025391] [Ensembl]; The gene Sarcoglycan δ is referred to in FlyBase by the symbol Dmel\Scgδ (CG14808, FBgn0025391). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of muscle. There is experimental evidence that it is involved in the biological process: heart contraction; sarcomere organization; mesoderm development. 8 alleles are reported. The phenotypes of these alleles are annotated with: dorsal medial muscle; adult heart; sarcomere; M band; indirect flight muscle. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Sarcoglycan complex subunit protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages. [FlyBase] Observation: Deletion of Scgdelta has detrimental effects on the flight muscles of adult animals and heart function. Median lifespan is reduced by 15-30% [17855453]. Interventions: Assays: Organismal Lifespan Median: -15 to -30 Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Inparanoids Edit \ Update (Admin) | Delete |
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