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Symbol: Hsp26 Name: Heat shock protein 26 Entrez gene ID: 39075 Ensembl gene ID: FBgn0001225 Species: Fly (Taxid: 7227) Functional description: Heat shock protein 26; Heat shock protein 26 [Source:FlyBase gene name;Acc:FBgn0001225] [Ensembl]; The gene Heat shock protein 26 is referred to in FlyBase by the symbol Dmel\Hsp26 (CG4183, FBgn0001225). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: determination of adult lifespan. 13 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Alpha crystallin/Heat shock protein; HSP20-like chaperone; Heat shock protein Hsp20. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [FlyBase] Observation: Overexpression of Hsp26 (by the UAS/GAL4 system) increases stress resistance and extends the mean lifespan by 30% [15308776]. Interventions: Assays: Organismal Lifespan Mean: +30 Classification: Type: References: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Orthologs Edit \ Update (Admin) | Delete |
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