Symbol: alpha-Man-I Name: alpha Mannosidase I Entrez gene ID: 31957 Ensembl gene ID: FBgn0259170 Species: Fly (Taxid: 7227) Observation: alpha-Man-I mutant fly exhibit enhanced resistance to paraquat and starvation an a 60% increase in mean lifespan for both sexes. After outcrossing, the mutant exhibit, under normal conditions, an increase in mean lifespan of 22% for females and 38% for males. Maximum lifespan is increased by 15%. alpha-Man-I RNAi knockdown results in a 39% increase in mean lifespan [19302370]. Interventions: Assays: Organismal Lifespan Mean: +22 to 60 Maximum: +15 Classification: Type: References: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
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