Symbol: BUB1B Name: budding uninhibited by benzimidazoles 1 homolog beta (yeast) Alias: BUBR1; MAD3L; Bub1A; SSK1 Entrez gene ID: 701 Ensembl gene ID: ENSG00000156970 Species: Human (Taxid: 9606) Function: Mitotic checkpoint protein that controls chromosome segregation and maintains genetic stability [9889005]. Observation: Mutations in BUB1B are associated with mosaic variegated aneuplody, a rare human syndrome characterized by aneuplodization, tumour predisposition and several progeroid traits, including short lifespan, growth and mental retardation, cataracts and facial dysmorphisms [16411201; 15475955; 20651707]. Assays: Organismal Lifespan Classification: References: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
Comment on This Data Unit