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Symbol: GPD1 Name: Glycerol-3-Phosphate Dehydrogenase 1 Entrez gene ID: 851539 Ensembl gene ID: YDL022W Species: Yeast (Taxid: 4932) Functional description: Gpd1p; NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p [Source:SGD;Acc:S000002180] [Ensembl] Observation: GPD1 deletion shortens replicative lifespan by 25% and prevents lifespan extension by high osmolarity [12391171]. Transcripational regulation of GPD1 by osmotic stress requires HOG1 [8196651]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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