Symbol: zyg-11 Name: ZYGote defective: embryonic lethal Alias: ZYGote defective: embryonic lethal family member (zyg-11);WBGENE00006996 Entrez gene ID: 174284 Ensembl gene ID: C08B11.1 Species: Worm (Taxid: 6239) Functional description: Acts as target recruitment subunit in the E3 ubiquitin ligase complex zyg-11-cul-2-elc-1. Required for metaphase to anaphase transition and M phase exit at meiosis II. Regulates polarity establishment. [UniProt] Observation: zyg-11 RNAi in the adulthood extends the lifespan [New longevity regulators]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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