ATG11

Symbol: ATG11
Name: AuTophaGy related 11
Alias: CVT9
Entrez gene ID: 856162
Ensembl gene ID: YPR049C
Species: Yeast (Taxid: 4932)

Functional description:
Atg11p; Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; directs receptor-bound cargo to the phagophore assembly site (PAS) for packaging into vesicles; required for recruiting other proteins to the (PAS) [Source:SGD;Acc:S000006253] [Ensembl]

Observation:

ATG11 deletion extends replicative lifespan under AL and abrogates DR-lifespan extension [18690010].



Interventions:
  • ATG11 deletion

  • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene
  • DR-Essential


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • ATG11 (4932)
  • KLLA0B12133g (28985)
  • AGOS_ADL307W (33169)



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