| 855126 | 851542 | 855126; YMR100W; MUB1 | 851542; YDL020C; RPN4; UFD5; SON1 | physical; direct | Biochemical Activity | physical association; direct interaction | Ubiquitination; Proteolytic Processing | 4932 | 4932 | 18070918 | BioGRID | 8 |
| 1642 | 11104 | 1642; DDB1; DDBA; XAP1; XPE; UV-DDB1; XPE-BF; XPCE; 11104; KATNA1 | 11104; KATNA1; 1642; DDB1; DDBA; XAP1; XPE; UV-DDB1; XPE-BF; XPCE | physical; direct | Biochemical Activity; Affinity Capture-Western | direct interaction | Ubiquitination; Phosphorylation | 9606 | 9606 | 19287380 | BioGRID | 7 |
| 9730 | 11104 | 9730; VprBP; DCAF1; 11104; KATNA1 | 11104; KATNA1; 9730; VprBP; DCAF1 | physical; direct | Biochemical Activity; Reconstituted Complex; Affinity Capture-Western | direct interaction; physical association | Ubiquitination; Phosphorylation | 9606 | 9606 | 19287380 | BioGRID | 8 |
| 56852 | 5111 | 56852; RAD18; RNF73 | 5111; PCNA | physical; direct | Biochemical Activity; Affinity Capture-Western; Reconstituted Complex | direct interaction; physical association | Ubiquitination; Phosphorylation | 9606 | 9606 | 18245774; 17108083; 21967848; 21227930; 17720710; 15359278; 20064529; 20600238; 21858012; 20675655 | BioGRID | 17 |
| 51366 | 11104 | 51366; UBR5; EDD; DD5; EDD1; HYD; 11104; KATNA1 | 11104; KATNA1; 51366; UBR5; EDD; DD5; EDD1; HYD | physical; direct | Biochemical Activity; Affinity Capture-Western | direct interaction; physical association | Ubiquitination; Phosphorylation | 9606 | 9606 | 19287380 | BioGRID | 8 |
| 8445 | 11104 | 8445; DYRK2; 11104; KATNA1 | 11104; KATNA1; 8445; DYRK2 | physical; direct | Biochemical Activity; Affinity Capture-Western | direct interaction; physical association | Ubiquitination; Phosphorylation | 9606 | 9606 | 19287380 | BioGRID | 8 |
| 55294 | 898 | 55294; FBXW7; SEL-10; FBW7; FBX30; FBW6; CDC4; FBXO30; SEL10; AGO; FBXW6; 898; CCNE1; CCNE | 898; CCNE1; CCNE; 55294; FBXW7; SEL-10; FBW7; FBX30; FBW6; CDC4; FBXO30; SEL10; AGO; FBXW6 | physical; direct | Biochemical Activity; Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Protein-peptide | physical association; direct interaction; association | Ubiquitination; No Modification | 9606 | 9606 | 11565034; 17298674; 16338364; 18559665; 15364936; 22388891; 15980150; 16818231; 17434132; 17646408; 14536078 | BioGRID | 19 |
| 4193 | 7157 | 4193; MDM2; hdm2; HDMX; 7157; TP53; p53; TRP53; LFS1 | 7157; TP53; p53; TRP53; LFS1; 4193; MDM2; hdm2; HDMX | physical; direct; genetic | Affinity Capture-Western; Phenotypic Suppression; Two-hybrid; Biochemical Activity; Reconstituted Complex; Protein-peptide; Affinity Capture-RNA; Co-crystal Structure; PCA; Co-localization; Protein-RNA; Affinity Capture-MS; Co-fractionation; FRET; Far Western | physical association; direct interaction; colocalization; additive genetic interaction defined by inequality; association; synthetic genetic interaction defined by inequality; suppressive genetic interaction defined by inequality | Ubiquitination; Nedd(Rub1)ylation; Deacetylation; | 9606 | 9606 | 20235143; 16201274; 17318220; 21471462; 16338390; 15242646; 22374672; 14559824; 18234963; 19033382; 19411066; 21261729; 18604177; 9582019; 16159876; 17875722; 19305137; 16870621; 11839577; 16905769; 10561590; 12381304; 19106616; 8875929; 22032989; 18467333; 19081178; 17426254; 15824742; 18815136; 22474335; 11112690; 18981217; 18813780; 22301280; 22266868; 22920093; 22912717; 10435614; 22916255; 22948151; 22331460; 22819825; 16173922; 16678796; 15144954; 20639885; 20705607; 15001357; 11714701; 19160491; 15094782; 11697899; 20234175; 11285227; 17116689; 15950904; 16414131; 17848574; 22737255; 10889512; 10640350; 22389628; 16861890; 10827196; 17159902; 21584881; 18541670; 20962272; 22444248; 9450543; 17666403; 22575647; 22487680; 22525275; 11486026; 15013777; 22227409; 20659896; 21572037; 20694676; 21098709; 15058298; 18566590; 18264029; 21084564; 20542919; 21965653; 22103682; 22157679; 21925390; 21316347; 21060154; 22124327; 20124408; 20484049; 21478269; 21986495; 20395212; 20479273; 19816404; 19857530; 17290220; 19656744; 21084285; 20173098; 16845383; 21887275; 19568783; 17301054; 21088494; 20657550; 19411846; 19837670; 11597128; 20588255; 10488081; 11046142; 21454483; 11431470; 11713288; 11925449; 15908921; 15154850; 12944468; 14596917; 15064742; 16624812; 15308643; 15933712; 16023600; 16107876; 19085961; 19303885; 16547496; 16579792; 16857591; 16866370; 17139261; 17380154; 17525743; 17908790; 18485870; 18172499; 18309296; 18332869; 18665269; 19098711; 12208736; 7686617; 9529249; 10722742; 9809062; 14612427; 11709713; 14671306; 8058315; 7689721; 22588298; 17056014; 15053879; 17302414; 15558054; 9278461; 11178989; 16432196; 19153082; 12842086; 11351297; 9363941; 12552135; 15848166; 14741215; 14499615; 17616658; 1614537; 9223638; 22914926; 22318540; 15604276; 21268072; 16152627; 19941302; 22366412; 16055726; 16215989; 21075307; 19357310; 22266850; 22391559; 12897156; 22083959; 22084066; 22411991; 19332559; 21071676; 21317885; 20847049; 21149449; 20174603; 18061646; 21132010; 21750659; 17268548; 17297477; 21726810; 21465263; 19590512; 20959462; 11572869; 9824166; 9724739; 20570896; 10347217; 10980696; 11094089; 11384992; 11562347; 11744695; 12167711; 12612087; 14702041; 15122315; 15210108; 15295102; 15542844; 19223463; 16964247; 17098746; 17470788; 17363365; 17369817; 17591690; 17936559; 18223694; 19071110; 19166840; 19188367; 9271120; 10766163; 12426395; 12620407; 12915590 | BioGRID | 259 |
| 4193 | 4193 | 4193; MDM2; hdm2; HDMX | 4193; MDM2; hdm2; HDMX | physical; direct | Affinity Capture-MS; Affinity Capture-Western; Two-hybrid; Protein-peptide; Reconstituted Complex; Biochemical Activity; Co-fractionation; Co-crystal Structure | physical association; direct interaction; association; additive genetic interaction defined by inequality | Ubiquitination; Nedd(Rub1)ylation | 9606 | 9606 | 17373842; 16905769; 22493164; 17426254; 15001357; 15950904; 22333590; 17170710; 18264029; 21060154; 20484049; 20479273; 19619542; 21084285; 19683495; 16845383; 17301054; 14596917; 16714300; 16803902; 16965791; 17936559; 19166840; 10722742 | BioGRID | 33 |
| 850819 | 851424 | 850819; YLR128W; DCN1; 851424; YDL132W; CDC53 | 851424; YDL132W; CDC53; 850819; YLR128W; DCN1 | physical; direct; genetic | Reconstituted Complex; Affinity Capture-Western; Two-hybrid; Biochemical Activity; Co-purification; Synthetic Lethality | direct interaction; suppressive genetic interaction defined by inequality; physical association; colocalization; association | Ubiquitination; Nedd(Rub1)ylation | 4932 | 4932 | 19942853; 20832729; 18206966; 15988528; 10688190 | BioGRID | 16 |
| 7128 | 8737 | 7128; RP11-356I2.3; TNFAIP3; OTUD7C; TNFA1P2; A20; 8737; RIPK1; RIP1; RIP | 8737; RIPK1; RIP1; RIP; 7128; RP11-356I2.3; TNFAIP3; OTUD7C; TNFA1P2; A20 | physical; direct | Biochemical Activity; Affinity Capture-Western | direct interaction; physical association | Ubiquitination; Deubiquitination | 9606 | 9606 | 22585859; 15258597; 18246070; 19131965 | BioGRID | 11 |
| 7322 | 7316 | 7322; UBE2D2; UBC4; E2(17)KB2; PUBC1; UBC4/5; UBCH5B; 7316; UBC; HMG20 | 7316; UBC; HMG20; 7322; UBE2D2; UBC4; E2(17)KB2; PUBC1; UBC4/5; UBCH5B | physical; direct | Biochemical Activity; Co-crystal Structure; Affinity Capture-Western; Reconstituted Complex; Affinity Capture-MS | direct interaction; physical association; association | Ubiquitination; Deubiquitination | 9606 | 9606 | 22496338; 22902369; 18264111; 12524449; 22325355; 20152160; 22505724; 17203973; 21906983; 21890473; 21139048 | BioGRID | 19 |
| 51343 | 890 | 51343; FZR1; HCDH1; FZR2; HCDH; CDH1; CDC20C; FZR | 890; CCNA2; CCNA; CCN1 | physical; direct | Biochemical Activity | colocalization; direct interaction | Ubiquitination; Acetylation | 9606 | 9606 | 18485873; 19483727 | BioGRID | 9 |
| 331 | 5414 | 331; RP1-315G1.5; XIAP; MIHA; XLP2; hIAP-3; BIRC4; API3; IAP-3; ILP1; hIAP3; 5414; hucep-7; SEPT4; hCDCREL-2; ARTS; MART; BRADEION; SEP4; PNUTL2; H5; CE5B3 | 5414; hucep-7; SEPT4; hCDCREL-2; ARTS; MART; BRADEION; SEP4; PNUTL2; H5; CE5B3; 331; RP1-315G1.5; XIAP; MIHA; XLP2; hIAP-3; BIRC4; API3; IAP-3; ILP1; hIAP3 | physical; direct | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex | physical association; direct interaction | Ubiquitination | 9606 | 9606 | 21869827; 22185822; 21185211 | BioGRID | 9 |
| 81603 | 6885 | 81603; RP11-47A8.4; TRIM8; RNF27; GERP; 6885; RP1-154G14.1; MAP3K7; TAK1; TGF1a; MEKK7 | 6885; RP1-154G14.1; MAP3K7; TAK1; TGF1a; MEKK7; 81603; RP11-47A8.4; TRIM8; RNF27; GERP | physical; direct | Biochemical Activity; Affinity Capture-Western | physical association | Ubiquitination | 9606 | 9606 | 22084099 | BioGRID | 6 |
| 83737 | 6416 | 83737; ITCH; dJ468O1.1; AIP4; AIF4; NAPP1; 6416; MAP2K4; SAPKK1; JNKK1; SERK1; PRKMK4; SAPKK-1; SEK1; MKK4; MAPKK4; MEK4; JNKK | 6416; MAP2K4; SAPKK1; JNKK1; SERK1; PRKMK4; SAPKK-1; SEK1; MKK4; MAPKK4; MEK4; JNKK; 83737; ITCH; dJ468O1.1; AIP4; AIF4; NAPP1 | physical; direct | Biochemical Activity; Reconstituted Complex; Affinity Capture-Western | direct interaction; physical association | Ubiquitination | 9606 | 9606 | 19737936 | BioGRID | 7 |
| 997 | 26272 | 997; CDC34; UBE2R1; UBC3; UBCH3; E2-CDC34 | 26272; FBXO4; FBX4 | physical; direct | Biochemical Activity | direct interaction | Ubiquitination | 9606 | 9606 | 10531035 | BioGRID | 6 |
| 856862 | 854114 | 856862; YER125W; RSP5; UBY1; SMM1; MUT2; NPI1; MDP1 | 854114; YOL043C; NTG2; SCR2 | physical; direct | Biochemical Activity | direct interaction | Ubiquitination | 4932 | 4932 | 17551511 | BioGRID | 6 |
| 331 | 56616 | 331; RP1-315G1.5; XIAP; MIHA; XLP2; hIAP-3; BIRC4; API3; IAP-3; ILP1; hIAP3; 56616; hCG_1782202; DIABLO; DFNA64; DIABLO-S; SMAC; SMAC3 | 56616; hCG_1782202; DIABLO; DFNA64; DIABLO-S; SMAC; SMAC3; 331; RP1-315G1.5; XIAP; MIHA; XLP2; hIAP-3; BIRC4; API3; IAP-3; ILP1; hIAP3 | physical; direct | Reconstituted Complex; Affinity Capture-Western; Co-crystal Structure; Protein-peptide; Affinity Capture-MS; Biochemical Activity; Far Western | direct interaction; physical association; colocalization | Ubiquitination | 9606 | 9606 | 14512414; 19667203; 11606597; 17179183; 17724022; 11140637; 11257230; 11257231; 19153467; 11602612; 15650747; 15507451; 11801603; 20957035; 15200957; 19506082; 15781261; 15300255; 12525502; 14523016; 15178455; 16282325; 11604410; 10929712; 15280366; 12511567; 12218061; 11242052; 15541727; 12660240 | BioGRID | 37 |
| 25897 | 6647 | 25897; RNF19A; DORFIN; RNF19 | 6647; SOD1; homodimer; IPOA; ALS; ALS1; SOD; hSod1 | physical; direct | Affinity Capture-Western; Biochemical Activity | physical association; direct interaction | Ubiquitination | 9606 | 9606 | 17157513; 12145308; 17666395 | BioGRID | 9 |
| 64682 | 891 | 64682; ANAPC1; APC1; MCPR; TSG24 | 891; CCNB1; CCNB | physical; direct | Biochemical Activity | synthetic genetic interaction defined by inequality; direct interaction | Ubiquitination | 9606 | 9606 | 22193957; 20080579 | BioGRID | 8 |
| 850597 | 851691 | 850597; YFR036W; CDC26; HIT3; SCD26 | 851691; YDR113C; PDS1 | physical; direct | Biochemical Activity | physical association | Ubiquitination | 4932 | 4932 | 16364911 | BioGRID | 6 |
| 83737 | 7316 | 83737; ITCH; dJ468O1.1; AIP4; AIF4; NAPP1; 7316; UBC; HMG20 | 7316; UBC; HMG20; 83737; ITCH; dJ468O1.1; AIP4; AIF4; NAPP1 | physical; direct | Biochemical Activity; Affinity Capture-Western; Reconstituted Complex; Affinity Capture-MS | physical association; direct interaction | Ubiquitination | 9606 | 9606 | 22496338; 20504295; 19808964; 20818436; 19341794; 20484045; 17013377; 17038327; 17719543; 22505724; 22053931; 21906983; 21890473; 21139048; 20972266; 21987572; 20639865; 19343052 | BioGRID | 24 |
| 852881 | 855743 | 852881; YGL003C; CDH1; HCT1 | 855743; YNR009W; NRM1 | physical; direct | Biochemical Activity | direct interaction | Ubiquitination | 4932 | 4932 | 21562221 | BioGRID | 6 |
| 997 | 4792 | 997; CDC34; UBE2R1; UBC3; UBCH3; E2-CDC34 | 4792; NFKBIA; IKBA; MAD-3; NFKBI | physical; direct | Biochemical Activity | direct interaction | Ubiquitination | 9606 | 9606 | 20347421 | BioGRID | 6 |
