5111 | 79915 | 5111; PCNA | 79915; ATAD5; ELG1; C17orf41; FRAG1 | physical; direct | Affinity Capture-Western; Reconstituted Complex | synthetic genetic interaction defined by inequality; suppressive genetic interaction defined by inequality | — | 9606 | 9606 | 20147293 | BioGRID | 6 |
6720 | 51586 | 6720; SREBF1; SREBP-1c; bHLHd1; SREBP1; 51586; MED15; CTG7A; CAG7A; TNRC7; ARC105; TIG1; TIG-1; PCQAP | 51586; MED15; CTG7A; CAG7A; TNRC7; ARC105; TIG1; TIG-1; PCQAP; 6720; SREBF1; SREBP-1c; bHLHd1; SREBP1 | physical; direct | Reconstituted Complex; Co-crystal Structure; Affinity Capture-MS; Affinity Capture-Western; Co-localization | synthetic genetic interaction defined by inequality; physical association; direct interaction; association | — | 9606 | 9606 | 16799563; 11834832; 20534441; 10235267 | BioGRID | 11 |
3638 | 22937 | 3638; INSIG1; CL-6; CL6 | 22937; PSEC0227; SCAP | physical; direct | Affinity Capture-Western | synthetic genetic interaction defined by inequality; physical association; additive genetic interaction defined by inequality | — | 9606 | 9606 | 12242332; 17043353; 18835813; 12842885 | BioGRID | 10 |
81620 | 4175 | 81620; CDT1; RIS2; DUP | 4175; MCM6; P105MCM; Mis5; MCG40308 | physical; direct | Co-crystal Structure; Affinity Capture-Western; Affinity Capture-MS | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 22140117; 18184650; 18162579 | BioGRID | 8 |
1499 | 5308 | 1499; OK/SW-cl.35; CTNNB1; CTNNB; 5308; PITX2; RGS; IHG2; RIEG; RS; IGDS; IRID2; RIEG1; Otlx2; ARP1; PTX2; IDG2; Brx1; IGDS2 | 5308; PITX2; RGS; IHG2; RIEG; RS; IGDS; IRID2; RIEG1; Otlx2; ARP1; PTX2; IDG2; Brx1; IGDS2; 1499; OK/SW-cl.35; CTNNB1; CTNNB | physical; direct | Affinity Capture-Western | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 12464179 | BioGRID | 6 |
2697 | 56893 | 2697; GJA1; DFNB38; HSS; CX43; GJAL; ODDD; AVSD3; 56893; RP11-336K24.8; UBQLN4; UBIN; C1orf6; A1U; CIP75 | 56893; RP11-336K24.8; UBQLN4; UBIN; C1orf6; A1U; CIP75; 2697; GJA1; DFNB38; HSS; CX43; GJAL; ODDD; AVSD3 | physical; direct | Affinity Capture-Western | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 18079109; 20940304 | BioGRID | 7 |
378708 | 2175 | 378708; APITD1; MHF1; CENPS; FAAP16; CENP-S | 2175; FANCA; FANCH; FA1; FA; FA-H; FAA; FACA; FAH | physical; direct | Co-localization; Affinity Capture-Western | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 20347429 | BioGRID | 6 |
8243 | 149708 | 8243; RP6-29D12.1; SMC1A; SMC1; CDLS2; SMCB; SMC1alpha; SMC1L1; DXS423E; SB1.8; 149708; UNQ3036/PRO9842; WFDC5; WAP1; PRG5; dJ211D12.5 | 149708; UNQ3036/PRO9842; WFDC5; WAP1; PRG5; dJ211D12.5; 8243; RP6-29D12.1; SMC1A; SMC1; CDLS2; SMCB; SMC1alpha; SMC1L1; DXS423E; SB1.8 | physical; direct | Affinity Capture-Western; Affinity Capture-MS | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 17112726; 17113138 | BioGRID | 7 |
6530 | 6622 | 6530; SLC6A2; NET; SLC6A5; NAT1; NET1; 6622; SNCA; PARK1; PD1; PARK4; NACP | 6622; SNCA; PARK1; PD1; PARK4; NACP; 6530; SLC6A2; NET; SLC6A5; NAT1; NET1 | physical; direct | Affinity Capture-Western | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 18331289 | BioGRID | 6 |
48 | 26234 | 48; RP11-334P12.1; ACO1; ACONS; IRP1; IREBP1; IREB1; IREBP; 26234; FBXL5; FLR1; FBL5; FBL4 | 26234; FBXL5; FLR1; FBL5; FBL4; 48; RP11-334P12.1; ACO1; ACONS; IRP1; IREBP1; IREB1; IREBP | physical; direct | Affinity Capture-Western | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 19762596 | BioGRID | 6 |
5241 | 8850 | 5241; PGR; NR3C3; PR | 8850; KAT2B; P; PCAF; CAF; P/CAF | physical; direct | Reconstituted Complex; Affinity Capture-Western | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 9223281; 16728408 | BioGRID | 7 |
4609 | 5701 | 4609; MYC; MRTL; c-Myc; bHLHe39 | 5701; PSMC2; S7; Nbla10058; MSS1 | genetic; direct; physical | Dosage Lethality; Affinity Capture-MS | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 22623531; 17314511 | BioGRID | 8 |
283989 | 80746 | 283989; TSEN54; PCH4; PCH2A; sen54; SEN54L; 80746; TSEN2; SEN2; SEN2L; PCH2B | 80746; TSEN2; SEN2; SEN2L; PCH2B; 283989; TSEN54; PCH4; PCH2A; sen54; SEN54L | physical; direct | Affinity Capture-MS | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 15109492 | BioGRID | 6 |
23024 | 4593 | 23024; PDZRN3; SEMACAP3; LNX3; 4593; RP11-104M22.1; MUSK | 4593; RP11-104M22.1; MUSK; 23024; PDZRN3; SEMACAP3; LNX3 | physical; direct | Affinity Capture-Western | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 17576800 | BioGRID | 6 |
7398 | 79915 | 7398; USP1; UBP; 79915; ATAD5; ELG1; C17orf41; FRAG1 | 79915; ATAD5; ELG1; C17orf41; FRAG1; 7398; USP1; UBP | physical; direct | Affinity Capture-Western; Affinity Capture-MS | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 20147293; 21555454 | BioGRID | 7 |
2177 | 3014 | 2177; FANCD2; FA4; FA-D2; FACD; FANCD; FAD2; FAD; 3014; H2AFX; H2A/X; H2AX; H2A.X | 3014; H2AFX; H2A/X; H2AX; H2A.X; 2177; FANCD2; FA4; FA-D2; FACD; FANCD; FAD2; FAD | physical; direct | Affinity Capture-Western | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 17304220 | BioGRID | 6 |
11183 | 1398 | 11183; MAP4K5; GCKR; KHS1; KHS; MAPKKKK5; 1398; CRK; p38; CRKII | 1398; CRK; p38; CRKII; 11183; MAP4K5; GCKR; KHS1; KHS; MAPKKKK5 | physical; direct | Affinity Capture-Western; Affinity Capture-MS | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 10648385; 19380743 | BioGRID | 7 |
207 | 5464 | 207; AKT1; RAC-ALPHA; PRKBA; PKB; AKT; PKB-ALPHA; RAC; 5464; RP11-367H5.1; PPA1; PP; SID6-8061; IOPPP; PP1 | 5464; RP11-367H5.1; PPA1; PP; SID6-8061; IOPPP; PP1; 207; AKT1; RAC-ALPHA; PRKBA; PKB; AKT; PKB-ALPHA; RAC | physical; direct | Affinity Capture-Western | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 16186112 | BioGRID | 6 |
4609 | 23020 | 4609; MYC; MRTL; c-Myc; bHLHe39 | 23020; SNRNP200; RP33; ASCC3L1; HELIC2; BRR2; U5-200KD | genetic; direct; physical | Dosage Lethality; Affinity Capture-MS | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 22623531; 17314511; 17353931 | BioGRID | 9 |
4609 | 83903 | 4609; MYC; MRTL; c-Myc; bHLHe39 | 83903; GSG2; HASPIN | genetic; direct; physical | Dosage Lethality; Affinity Capture-MS | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 22623531; 17314511 | BioGRID | 8 |
2547 | 8837 | 2547; CTA-216E10.7; XRCC6; CTC75; ML8; CTCBF; KU70; TLAA; G22P1; 8837; CFLAR; FLAME-1; c-FLIPR; FLIP; CASH; c-FLIPL; c-FLIP; FLAME; c-FLIPS; I-FLICE; CLARP; Casper; FLAME1; CASP8AP1; MRIT | 8837; CFLAR; FLAME-1; c-FLIPR; FLIP; CASH; c-FLIPL; c-FLIP; FLAME; c-FLIPS; I-FLICE; CLARP; Casper; FLAME1; CASP8AP1; MRIT; 2547; CTA-216E10.7; XRCC6; CTC75; ML8; CTCBF; KU70; TLAA; G22P1 | physical; direct | Affinity Capture-Western | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 22322857 | BioGRID | 6 |
3065 | 57708 | 3065; RP4-811H24.2; HDAC1; HD1; GON-10; RPD3; RPD3L1; 57708; RP5-944N15.1; MIER1; MI-ER1; ER1; hMI-ER1 | 57708; RP5-944N15.1; MIER1; MI-ER1; ER1; hMI-ER1; 3065; RP4-811H24.2; HDAC1; HD1; GON-10; RPD3; RPD3L1 | physical; direct | Affinity Capture-Western; Reconstituted Complex | synthetic genetic interaction defined by inequality; physical association | — | 9606 | 9606 | 12482978 | BioGRID | 6 |
11140 | 1019 | 11140; CDC37; P50CDC37; 1019; CDK4; CMM3; PSK-J3 | 1019; CDK4; CMM3; PSK-J3; 11140; CDC37; P50CDC37 | physical; direct | PCA; Reconstituted Complex; Co-fractionation; Two-hybrid; Affinity Capture-Western; Affinity Capture-MS | synthetic genetic interaction defined by inequality; direct interaction; physical association; association | — | 9606 | 9606 | 21675959; 8666233; 8703009; 11867521; 9150368; 17353931 | BioGRID | 13 |
7535 | 7846 | 7535; ZAP70; TZK; ZAP-70; SRK; STD; 7846; TUBA1A; TUBA3; LIS3; B-ALPHA-1 | 7846; TUBA1A; TUBA3; LIS3; B-ALPHA-1; 7535; ZAP70; TZK; ZAP-70; SRK; STD | physical; direct | Affinity Capture-Western; Reconstituted Complex | synthetic genetic interaction defined by inequality; direct interaction; physical association | — | 9606 | 9606 | 8530437 | BioGRID | 7 |
6597 | 6772 | 6597; SMARCA4; SNF2; hSNF2b; SNF2-BETA; SWI2; BAF190; SNF2LB; RTPS2; BRG1; SNF2L4; 6772; STAT1; CANDF7; ISGF-3; STAT91 | 6772; STAT1; CANDF7; ISGF-3; STAT91; 6597; SMARCA4; SNF2; hSNF2b; SNF2-BETA; SWI2; BAF190; SNF2LB; RTPS2; BRG1; SNF2L4 | physical; direct | Co-localization; Affinity Capture-Western | synthetic genetic interaction defined by inequality; direct interaction; physical association | — | 9606 | 9606 | 16195385; 21079652; 20353823 | BioGRID | 9 |