| Collaborative Knowledge-Management | 1 | 2 | Kulaga; Wuttke | We will establish **new kind of collaboration models** between people (including Researches) and in **Graph representation of knowledge**.
``Collaboration and knowledge-management websystems`` are the clue that **increases collective intelligence*... |
| Logo Contest | 1 | 3 | Silvennoinen; Flatt; Maidano | The individual **longevity parties** operate under the ``banner`` of the International Longevity Alliance (**ILA**). However, the ILA does not yet have such an unifying banner.
The logo will be utilized **cross-nationally** with only minor modific... |
| Curing Cancer | 1 | 3 | Coles; Debonneuil; Stambler | **Cancer** is ``function of Aging`` and its ``elimination is necessary`` for achieving longevity. Different **experimental approaches** can highly effectively **cure** or at least regress defined types of **Cancers**.
``Dr. Stephen Coles`` is an i... |
| Crowd Funding | 1 | 4 | Kulaga; Khaltourina; Katiyar; Xu | Crowd funding/financing is the collaborative effort of individuals who network and **pool** their **money** usually via Internet **to support** the **effort of a group/organization**.
It therefore provides a powerful **alternative resource to gran... |
| Grant Writing | 1 | 2 | Debonneuil; Stambler | Grant writing is the practice of ``completing an application process for funding`` provided by institution like government department, corporation, foundation or trust.
In the name of the International Longevity Alliance there shall be **assistanc... |
| Circadian Rhythm | 2 | 4 | Kapahi; Magalhaes; Wuttke; Katewa | Most animals have rest/activity/rhythms that are powered by an endogenous timing mechanism, the circadian system. With aging the rhythm becomes weaker [23223368].
Middle aged flies exhibit reduced activity level in comparison with young controls. ... |
| Denigma | 5 | 9 | Fuellen; Magalhaes; Debonneuil; Kulaga; Wuttke; Adams; Borisoglebsky; Fortney; Hall | Denigma is the digital Enigma destined to decipher biological phenomena. All information of an organism is encoded in its genome and can be decrypted via the combined effort of humans and machines. For this, Denigma was build for.
Specifically, Deni... |
| Pentose Phosphate Pathway | 2 | 3 | Magalhaes; Wuttke; Tang | The pentose phosphate pathway chiefly generates reduction equivalents in the form of NADPH:
3 G6P + 6 NADPH+ + 3 H2O = 6 NADPH + 6 H+ + 3 CO2 + 2 F6P + GAP
6 equivalents of NADPH is quite a lot for just three sugars. NADPH might scavenge ROS.
... |
| Tissue-Specific DR-Effects | 2 | 4 | Kapahi; Magalhaes; Wuttke; Li |
:Abstract: A restricted diet without malnutrition highly effectively counteracts ageing in several species and extends robustly their lifespan. How lifespan is extended remains enigmatic. We utilized tissue-specific gene expression data in *Droso... |
| Gerontology | 2 | 0 | | The ``Gerontology Ontology`` (the Ontology for Aging and Longevity, ``GERO``) is a mid-level ontology representing aging-related phenomena from the molecular and cellular levels to the social and demographic level. It aims to support gerontological ... |
| Circadian Clock Controls Ageing | 2 | 3 | Magalhaes; Wuttke; Wood |
:Abstract: Dietary restriction without malnutrition delays ageing and extends lifespan, but the molecular mechanism is still unknown. Ageing gene expression changes originate from development and growth cessation, are modulated by diet, and manip... |
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