Polymorphism: XbaI
Variant Type: SNP
Location: 2p24-p23
Factor:
- Symbol: APOB
- Name: apolipoprotein B (including Ag(x) antigen)
- Entrez ID: 338
- Ensembl ID: ENSG00000084674
Factors:
APOB
apolipoprotein B (including Ag(x) antigen)
(
338
/
ENSG00000084674
)
Description:
Rsid is rs693
Allele frequencies didn`t differ significantly between age groups.
However X+X+ (genotype) were enriched in long-living people
Ethnicity:
Chinese
Age of cases: > 90 baseline, Mean age 97 +/- 3
Longer lived allele: X+X+
Finding: Positive
Statistics
- Number of cases/controls: 191 (case) vs 53 (initial)
- Odds ratio: 1.296
- Odds ratio type: Longer
- p-value:
0.03
[0.03]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: Restrictive enzyme Xba I, Taq polymerase
Reference:
17393087: Correlation between haplotype of apolipoprotein B gene and natural longevity persons in Uygur nationality.
Choice: Clean
Created: July 2, 2013, 2:33 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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