Polymorphism: rs1042522
rs1042522
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 17p13.1
Factor:
- Symbol: TP53
- Name: tumor protein p53
- Entrez ID: 7157
- Ensembl ID: ENSG00000141510
Factors:
TP53
tumor protein p53
(
7157
/
ENSG00000141510
)
Description:
TP53*P72 allele negatively influences female life expectancy. Detailed OR information is as follows: Additive model: 0.574, Dominant model: 0.513
Ethnicity:
Italian
Age of cases: 91+, 73-91
Shorter lived allele: P
Finding: Positive
Statistics
- Number of cases/controls: 100 very old vs 280 old vs 189 young (initial)
- Odds ratio: 0.574
- p-value:
0.006
- Significant: Yes
Study Design
- Study type: Candidate Region/Gene
- Technology: PCR, restriction digest, gel electrophoresis
Reference:
23125046: TP53*P72 allele influences negatively female life expectancy in a population of central Italy: cross-sectional study and genetic-demographic approach analysis.
Choice: Curate
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.
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