Denigma
hevok @hevok September 21, 2012
#iPSC #markers #reprogramming #stem cells

Early Markers of Efficient Reprogramming

Expression profiling of genes associated with pluripotency revealed a early marker genes which determine whether a cell will be fully, partially or not reprogrammed. Around six days after the introduction of defined factors cells that were reprogrammed expressed Esrrb, Utf1, Lin28 and Dppa2 which themselves control the transcription factors involved in pluripotency.