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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs2682826 NOS1 0.589 321 vs 442 Italian 89-107 Candidate Region/Gene 23572278
rs6457452 HSP70-A1B 1.0 347 vs 238 American, Ashkenazi Jewish Minimum age 100 Candidate Region/Gene 17027907
-1377G/A FAS 0.106 50 vs 86 Italian 100.8 ± 1.8 (100 to 106) Candidate Region/Gene 11965496
rs10459953 0.522 321 vs 442 Italian 89-107 Candidate Region/Gene 23572278
IVS2nt-124 FASLG 0.315 50 vs 86 Italian 100.8 ± 1.8 (100 to 106) Candidate Region/Gene 11965496
rs10765518 Intergenic 1.08 7.5e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American C Genome-Wide Association Study 21782286
rs2297518 NOS2 0.066 321 vs 442 Italian 89-107 Candidate Region/Gene 23572278
IVS3nt-167 FASLG 0.462 50 vs 86 Italian 100.8 ± 1.8 (100 to 106) Candidate Region/Gene 11965496
rs10277237 0.805 321 vs 442 Italian 89-107 Candidate Region/Gene 23572278
192 PON1 1.26 0.007 Italian: 308 vs 579; Northern Irish: 296 vs 296 Irish Italian: Mean age 100.8 +/- 2.1; Northern Irish: Mean age 89.8 +/- 5.7 Q Candidate Region/Gene 15050299
rs1799983 NOS3 0.703 321 vs 442 Italian 89-107 Candidate Region/Gene 23572278
rs708272 CETP 1.0 12 vs 190 vs 105 Greek 99-111 Candidate Region/Gene 23389097
MNS16A TERT 0.75 0.019 200 vs 539 Italian 88+ MNS16A*L Candidate Region/Gene 23562826
rs5882 CETP 1.0 12 vs 190 vs 105 Greek 99-111 Candidate Region/Gene 23389097
rs6545764 Intergenic 1.17 8.75e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American T Genome-Wide Association Study 21782286
rs12778366 SIRT1 0.69 0.025 1390 Dutch 36 to 79 Candidate Region/Gene 23505545
H63D HFE 1.0 35 vs 106 91-105 Candidate Region/Gene 11857056
S65C HFE 1.0 35 vs 106 91-105 Candidate Region/Gene 11857056
rs7896005 SIRT1 0.0056 224 vs 293 170 vs 220 Caucasian Range: 90-103 A Candidate Region/Gene 21972126
rs3758391 SIRT1 1.45 0.026 246 vs 236 Chinese 71.2±7.1 years T Candidate Region/Gene 20633545
Q/H 95, rs2866164 0.0005 653 (197 m, 456 f) vs non-mentioned 564 (92 m, 472 f) vs 564___(Franch Caucasians) American, Caucasian Mean 100,8 Q95 G Genome-Wide Association Study 14615589
rs10256177 Intergenic 1.16 8.81e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American A Genome-Wide Association Study 21782286
rs3758391 SIRT1 1.0 223 vs 277 Chinese Average age 93 Candidate Region/Gene 23450480
rs4746720 SIRT1 1.35 0.022 246 vs 236 Chinese 71.2±7.1 years T Candidate Region/Gene 20633545
rs752766 Intergenic 0.0058 653 (197 m, 456 f) vs non-mentioned 564 (92 m, 472 f) vs 564___(Franch Caucasians) American, Caucasian Mean 100,8 Genome-Wide Association Study 14615589