Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs1043618 HSP70-A1A — 1.0 347 vs 238 — American, Ashkenazi Jewish Minimum age 100 — — Candidate Region/Gene 17027907
rs6457452 HSP70-A1B — 1.0 347 vs 238 — American, Ashkenazi Jewish Minimum age 100 — — Candidate Region/Gene 17027907
HRAS1 3'VNTR HRAS 1.13 0.551 234 vs 467 — Italian Minimum age 100 a3 non-a3 Candidate Region/Gene 11943467
rs1063539 ADIPOQ10 — 0.2 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs182052 ADIPOQ10 — 0.22 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs266729 ADIPOQ10 — 0.08 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs2755209 FOXO1 — 0.48 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs2721069 FOXO1 — 0.62 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs2755213 FOXO1 — 0.77 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs2764264 FOXO3 — 0.0002 213 vs 402 — Japanese minimum 95; mean 97.9 T — Candidate Region/Gene 18765803
rs13217795 FOXO3 — 0.0006 213 vs 402 — Japanese minimum 95; mean 97.9 T — Candidate Region/Gene 18765803
rs2802292 FOXO3 — 0.0001 213 vs 402 — Japanese minimum 95; mean 97.9 T — Candidate Region/Gene 18765803
rs7069102 SIRT1 — 0.84 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs10823112 SIRT1 — 0.44 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs1885472 SIRT1 — 0.71 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs8051232 COQ7 — 0.9 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs11074359 COQ7 — 0.43 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
rs7192898 COQ7 — 0.73 213 vs 402 — Japanese minimum 95; mean 97.9 — — Candidate Region/Gene 18765803
marker D4S1564 — — 0.044 308 — European min. age 98 for one sibling. 91+ males, 95+ females — — Genome-Wide Association Study 11526246
rs2866164 MTTP — 0.05 126 vs 288 — Ashkenazi Jewish median age = 97 CG/GG — Candidate Region/Gene 22496539
rs1800795 IL-6 — 0.007 323 (cases) vs 377 (initial) — Italian median age = 101 G C Candidate Region/Gene 11500818
rs10149689 TSHR 1.56 0.001 232 vs 163 — Ashkenazi Jewish Median age 97 A G Candidate Region/Gene 19837933
rs12050077 TSHR 1.68 0.0001 232 vs 163 — Ashkenazi Jewish Median age 97 G A Candidate Region/Gene 19837933
rs12050077 TSHR 1.32 0.01 366 vs 163 — Ashkenazi Jewish Median age 69 A G Candidate Region/Gene 19837933
rs10149689 TSHR 1.22 0.08 366 vs 163 — Ashkenazi Jewish Median age 69 A G Candidate Region/Gene 19837933