Denigma Buck Institute Health Extension
Polymorphism: DRB1/DQB1


Location: 6p21.3

Factor:
- Symbol: HLA
- Name: major histocompatibility complex, class I, B
- Entrez ID: 3106
- Ensembl ID: ENSG00000234745

Factors:
  • HLA major histocompatibility complex, class I, B ( 3106 / ENSG00000234745 )

    • Ethnicity: Chinese
    Age of cases: >90
    Shorter lived allele: non HLA-DRB1*04 or non HLA-DRB1*16 alleles
    Longer lived allele: HLA-DRB1*04, HLA-DRB1*16

    Statistics
    - Number of cases/controls: 20 vs 81 (initial)
    - Significant: yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    17364902: Molecular genetic studies on relationships among longevity, diseases, and HLA-DRB1/DQB1 allelic polymorphism.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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