Polymorphism: rs2542052
rs2542052
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 11q23.3
Factor:
- Symbol: APOC3
- Name: apolipoprotein C-III
- Entrez ID: 345
- Ensembl ID: ENSG00000110245
Description:
A multilocus PCR for 66 polymorphisms was performed in Askenazi Jews and found a significant correlation with longevity for the rs2542052 poymorphism.
Ethnicity:
Ashkenazi Jewish
Age of cases: Mean age 98.2
Shorter lived allele: A
Finding: Positive
Statistics
- Number of cases/controls: Centenarians (n = 213) their offspring (n = 216) vs 258 (initial)
- p-value:
0.0001
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Technology: Multilocus PCR
Reference:
16602826: Lipoprotein genotype and conserved pathway for exceptional longevity in humans.
Choice: Curate
Created: June 30, 2013, midnight
Updated: July 30, 2013, 6:01 p.m.
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