Polymorphism: rs1061581-rs1043618-rs2227956
rs1061581-rs1043618-rs2227956
(
SNPedia |
23andMe
)
Variant Type: Haplotype
Location: 6p21.3
Factors:
HSPA1A
heat shock 70kDa protein 1A
(
3303
/
ENSG00000204389
)
HSPA1B
heat shock 70kDa protein 1A
(
3303
/
ENSG00000204389
)
HSPA1L
heat shock 70kDa protein 1-like
(
3305
/
ENSG00000204390
)
Description:
Haplotype factors are in the following order: HSPA1B-HSPA1A-HSPA1L
Ethnicity:
Chinese
Age of cases: >90
Shorter lived allele: non A-G-C or non A-C-T haplotypes
Longer lived allele: A-C-T
Finding: Positive
Statistics
- Number of cases/controls: 191 vs 53 (initial)
- Odds ratio: 4.51
- p-value:
0.016
[0.016]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR based probes
Reference:
19840767: Interactive association of heat shock protein 70 genes variants with natural longevity in Xinjiang Hetian Uygur ethnicity.
Choice: Curate
Created: Aug. 11, 2013, 8:31 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
Edit
(
Admin) |
Delete