Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs1333049 — 0.64 0.001 80 (cases) vs 258 healthy young — Human 100–104 C — Candidate Region/Gene 20230275
rs16928120 — — 0.00057 1600 samples (cases and controls combined) — German, Italian — — — Candidate Region/Gene 19367319
rs4746720 — 1.35 0.022 246 vs 236 — Chinese 60-90 — C Candidate Region/Gene 20633545
rs7843014 — 0.37 0.001 175 vs 355 — Spanish 100-111 A C Candidate Region/Gene 24930376
rs4420638 — 0.85 0.176 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs1800624 — — 0.028 28 vs 56 — Caucasian 90+ non-AA AA Candidate Region/Gene 24284407
rs13306703 — — 0.764 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
rs1048310 — — 0.87 208 vs 399 — Japanese 95+ — — Candidate Region/Gene 23770741
rs6589722 — — 0.015 209 vs 402 — Japanese 95+ — — Candidate Region/Gene 23770741
rs10811661 — — 0.13 213 vs 402 — Japanese 95+ — — Candidate Region/Gene 23770741
rs2999131 — — 0.31 208 vs 391 — Japanese 95+ — — Candidate Region/Gene 23770741
rs4673 — 1.48 0.022 — — Russian — C T Candidate Region/Gene 23755540
rs1879417 — — 0.018 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
rs10459953 — — 0.522 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
rs10277237 — — 0.805 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
rs1799990 — — 1.0 150 vs 165 — Polish Centenarian — — Candidate Region/Gene 23406923
rs429358, rs7412 APOE 0.43 0.0006 114 vs 2071 — Irish >90 e4 e2 Candidate Region/Gene 11470126
HRAS1 LASS1 (CCT) APOE — 4.1e-05 147 vs 188 — Georgian — — — Candidate Region/Gene 20569235
rs429358, rs7412 APOE 0.75 0.005 2307 vs 764 — American, Danish Mean age 60.2 e4 e2 Candidate Region/Gene 23040522
rs2075650 APOE — 0.000527 1364 — American, British Age range 50-108; mean age at death 80.2 C T Candidate Region/Gene 22445811
rs449647 APOE 1.01 0.767 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs405509 APOE 1.18 0.027 597 vs 1275 418 vs 450 Sichuan 90+ — — Candidate Region/Gene 24924924
rs440446 APOE 1083.00 0.509 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs769448 APOE 1.09 0.66 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs769449 APOE 0.90 0.62 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
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  • 25 of 375 variants