| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| E2 / E3 / E4 | APOE | — | 1.2e-08 | 560 vs 560 | — | French | centenarians 100th year or beyond, mean age 103.1 | E4 | — | Candidate Region/Gene | 11280044 |
| HLA-DRB1 13 generic DRB1 alleles | HLA-DRB1 | 2.03 | 0.001 | 336 vs 2950 | 208 vs original 2950 | French | 100+ and 90+ siblings | non-DR11 alleles | DR11 | Candidate Region/Gene | 9425225 |
| rs4340 | ACE | 1.90 | 0.001 | 300 vs 160 | — | French | 100+ | I | D | Candidate Region/Gene | 8136829 |
| APOE e2/e4 | APOE | 2.00 | 0.001 | 300 vs 160 | — | French | 100+ | e4 | e2 | Candidate Region/Gene | 8136829 |
| apoAIV(360:His) | APOA4 | — | 0.005 | 119 (see notes) vs 264 | — | French | 74.29 ∓ 8.46 | ApoAIV-1_x000D_, by the order of the sentence - I'm assuming it's Glutamine = G | — | Candidate Region/Gene | 9533408 |
| HLA-DRB1 13 generic DRB1 alleles | HLA-DRB1 | 1.72 | 0.01 | 152 vs 2950 | 208 vs original 2950 | French | 100+ and 90+ siblings | non-DR7 alleles | DR7 | Candidate Region/Gene | 9425225 |
| HLA-DRB1 13 generic DRB1 alleles | HLA-DRB1 | 1.46 | 0.01 | 488 vs 2950 | 208 vs original 2950 | French | 100+ and 90+ siblings | non-DR13 alleles | DR13 | Candidate Region/Gene | 9425225 |
| rs1776180 | EXO1 | 1.39 | 0.01 | 395 vs 411 | 455 vs 109 | French, German | Mean age 101.3 | G | C | Candidate Region/Gene | 19698732 |
| rs1799752 | ACE | — | 0.025 | 394 vs 238 | — | French | 100.6 years | Insertion | — | Candidate Region/Gene | 9761238 |
| rs1801133 | MTHFR | — | 0.06 | 564 vs. 374 | — | French | mean age 100.71 | TT | CT, CC | Candidate Region/Gene | 9106548 |
| rs662 | PON1 | 1.06 | 0.11 | — | — | Danish, Dutch, French, German, Italian, Tatar | >/=80 | — | — | Candidate Region/Gene | 20362697 |
| I/D (insertion/deletion) | ACE | — | 0.33 | 560 vs 560 | — | French | centenarians 100th year or beyond, mean age 103.1 | — | — | Candidate Region/Gene | 11280044 |
| CYP2D6*3 | CYP2D6 | — | 1.0 | 552 vs 243 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| CYP2D6*4 | CYP2D6 | — | 1.0 | 523 vs 252 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| GSTM1 deletion | GSTM1 | — | 1.0 | 565 vs 229 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| NAT2*5A (C 481 T), NAT2*6A (G 590 A), NAT2*7A (G 857 A), and NAT2*14A (G 191 A) | NAT2 | — | 1.0 | 188 vs 88 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| - | PARP1 | — | 1.0 | 239 vs 198 | — | French | >100 | — | — | Candidate Region/Gene | 9587069 |
