| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs915179-rs2485662-rs4641-rs1468772 | LMNA | 1.56 | 2.5e-05 | 873 vs 443 | New England Centenarian Study (NECS) (N = 738), (ii) the Southern Italian Centenarian Study (SICS) (N = 905), (iii) France (N = 1103), and (iv) the Einstein Ashkenazi Longevity Study (N = 702) | American, Caucasian | Mean age 101.5 | — | GTCT | Candidate Region/Gene | 22340368 |
| rs3803304 | AKT1 | 0.48 | 0.00016 | 294 vs 603;279 vs 797;383 vs 363 | — | Caucasian | Mean age 95.3; 94.5; 97.7 | C | G | Candidate Region/Gene | 19489743 |
| rs1887922 | IDE | 2.02 | 0.0004 | 829 vs 1033 | — | Australian, Caucasian | Mixed | — | — | Candidate Region/Gene | 18448515 |
| rs429358, rs7412 | APOE | — | 0.0005 | 318 vs 350 | 376 vs 506 | American, Caucasian | Mean age 100,8 | e4 | e2 | Candidate Region/Gene | 18034366 |
| rs1805415 | PARP1 | 0.66 | 0.001 | 479 vs 900 | 388 vs 364 | African American, Caucasian | — | G,C | T | Candidate Region/Gene | 19249341 |
| rs1544410-rs17878969 | VDR | 15.30 | 0.001 | 104 vs 114 | — | Caucasian, Spaniard | >85 | non G-S haplotypes | G-S | Candidate Region/Gene | 20407924 |
| rs2251101 | IDE | 1.88 | 0.0011 | 829 vs 1033 | — | Australian, Caucasian | Mixed | — | — | Candidate Region/Gene | 18448515 |
| rs2940923 | GHR | 1.21 | 0.0013 | 306 vs 603;279 vs 797;383 vs 363 | — | Caucasian | 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 121 | — | — | Candidate Region/Gene | 19489743 |
| −438 G/A | TAFI | 0.53 | 0.003 | 2224 | — | American, Caucasian | 65+ | G (men) | — | Candidate Region/Gene | 15939070 |
| rs7896005 | SIRT1 | 2.38 | 0.003 | 224 vs 293 | 170 vs 220 | Caucasian, European | 90-103, 98+ (replication) | G | — | Candidate Region/Gene | 21972126 |
| rs2940935 | GHR | 1.24 | 0.0031 | 307 vs 603;279 vs 797;383 vs 363 | — | Caucasian | 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 122 | — | — | Candidate Region/Gene | 19489743 |
| rs7896005 | SIRT1 | — | 0.0056 | 224 vs 293 | 170 vs 220 | Caucasian | Range: 90-103 | A | — | Candidate Region/Gene | 21972126 |
| rs508641 | LMNA | — | 0.014 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs915179 | LMNA | — | 0.014 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs9282861 | SULT1A1 | — | 0.017 | 68 vs 49 | — | American, Caucasian | 70-99 | — | GG | Candidate Region/Gene | 9854023 |
| rs3814314 | LMNA | — | 0.017 | 873 vs 443 (initial) | New England Centenarian Study: 545 vs 193; French: 557 vs 546; Southern Italian Centenarian Study: 455 vs 450; Ashkenazi Jewish: 354 vs 348 (replication) | American, Caucasian | Mean age 101.5 | — | — | Candidate Region/Gene | 22340368 |
| rs4946935 | FOXO3A | 1.48 | 0.018 | 302 vs 603;279 vs 797;383 vs 363 | — | Caucasian | 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 117 | A | — | Candidate Region/Gene | 19489743 |
| rs1935949 | FOXO3A | 1.46 | 0.019 | 299 vs 603;279 vs 797;383 vs 363 | — | Caucasian | 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 114 | T | — | Candidate Region/Gene | 19489743 |
| rs2153960 | FOXO3A | 1.16 | 0.019 | 300 vs 603;279 vs 797;383 vs 363 | — | Caucasian | 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 115 | — | — | Candidate Region/Gene | 19489743 |
| rs2272037 | IGF1R | 1.19 | 0.021 | 316 vs 603;279 vs 797;383 vs 363 | — | Caucasian | 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 131 | — | — | Candidate Region/Gene | 19489743 |
| rs10014396 | SNCA | — | 0.021 | 769 total (see notes) | — | Caucasian | >90 (oldest age group) | C | — | Candidate Region/Gene | 22912757 |
| rs3778588 | FOXO3A | 1.22 | 0.023 | 301 vs 603;279 vs 797;383 vs 363 | — | Caucasian | 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 116 | — | — | Candidate Region/Gene | 19489743 |
| rs11568820-rs4516035-rs10735810-rs1544410-rs17878969 | VDR | 11.50 | 0.024 | 104 vs 114 | — | Caucasian, Spaniard | >85 | G-G-C-G-S | non G-G-C-G-S haplotypes | Candidate Region/Gene | 20407924 |
| rs2866164 | MTP | — | 0.024 | 318 vs 350 | 376 vs 506 | American, Caucasian | Mean age 100,8 | GG | — | Candidate Region/Gene | 18034366 |
| rs3775439 | SNCA | — | 0.025 | 769 total (see notes) | — | Caucasian | >90 (oldest age group) | A | — | Candidate Region/Gene | 22912757 |
