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Longevity DB
Genetic variants implicated in human longevity.
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African European
Australian
Canadian
English People
Finn
Georgian
Human
Israeli
Multiethnic
Pomeranian
Sichuan
Spanish
Terraner
Age, Gene/Environment Susceptibility -Reykjavik Study Cohort (Island)
American
African American
American (Caucasian)
Amish
Atherosclerosis Risk Communities Study Cohort
Baltimore Longitudinal Study of Ageing Cohort
Cardiovascular Health Study Cohort
Caucasians (USA)
CHS (USA)
Framingham Heart Study Cohort
Framingham Heart Offspring Study Cohort
Gaucha population (Native South American)
Gerorgia (US)
New England American
North American
Mexican
Mexican Mestizo (see notes)
Study of Osteoporotic Fractures Cohort
The Health, Aging and Body Composition (USA)
US North European
USA (Black and European)
USA (Casucasians)
USA (Framington Heart Study)
Arab
Israelis
Nigerian
Tunisian
Turkish
Asian
Chinese
Bama Chinese
Chuang Chinese
Dujiangyan Han Chinese
Guangxi Bama Chinese
Han
Kahzak
Northern Chinese
Shanghai Chinese
Shenyang Chinese
Southern Chinese
Uyghur
Xinjiang Hetian Uyghur
Zhuang
Bama Zhuang
Japanese
Okinawan
Tokyo Japanese
Korean
Australian (Caucasian)
Australian centenarians of Caucasian ancestry
Brazilian
Gaucha Brazilian
Caucasian
Caucasian (NECS cohort)
Caucasian north
mostly Caucasian
European
African/European
British
English
Central European
Polish
Croatian
Danish
Dutch
Leiden Population
Rotterdam Population
Eastern European
European and Caucasian (many different european countries)
European Caucasian (Portuguese
European-origin (Caucasian)
French
German
Study of Health in Pomerania (Germany)
Greek
Irish
Belfast Irish
Northern Irish
Italian
Calabrian
Central Italian
Continental Italian
Invecchiare nel Chianti Cohort
Northeastern Italian
Northern Italian
Lombardy region Northern Italian
Northerncentral Italian
Sardinian
Southern Italian
Apulian
Calabrian
Northern European
Finns
Southern Finns
Tampere Population
Scottish
Southeastern Europe
Bulgarian
Southern European
Swiss
Western European
Spaniard
Caucasian Spanish
Caucasians from the city of Lleida in northeast Spain
Northern Spaniard
Spanish Combined: Pyrenees and Ebro’s Valley
Swedish
White European
Female
Caucasian Women
Georgia
Hispanic
Jewish
Ashkenazi Jewish
European-American Ashkenazi Jewish
Jordanian
Louisiana
Male
Mixed
Mixed Non-Hisp White
Slavs
Soviet
Russian
St. Petersburg Russian
Tatar
Tartarish
Population:
+
-
French «
Danish (1)
Dutch (1)
German (13)
Italian (12)
Tatar (1)
Study type:
+
-
‑ (14)
Candidate Region/Gene (17)
Variant type:
+
-
SNP (2)
Variant effect:
+
-
Longevity‑Associated (15)
No Age Effect (18)
polymorphism
factor
odds ratio
pvalue
initial number
replication number
Population
age of cases
shorter lived allele
longer lived allele
study type
reference
rs4340
ACE
1.90
0.001
300 vs 160
—
French
100+
I
D
Candidate Region/Gene
8136829
APOE e2/e4
APOE
2.00
0.001
300 vs 160
—
French
100+
e4
e2
Candidate Region/Gene
8136829
apoAIV(360:His)
APOA4
—
0.005
119 (see notes) vs 264
—
French
74.29 ∓ 8.46
ApoAIV-1_x000D_, by the order of the sentence - I'm assuming it's Glutamine = G
—
Candidate Region/Gene
9533408
I/D (insertion/deletion)
ACE
—
0.33
560 vs 560
—
French
centenarians 100th year or beyond, mean age 103.1
—
—
Candidate Region/Gene
11280044
rs1799752
ACE
—
0.025
394 vs 238
—
French
100.6 years
Insertion
—
Candidate Region/Gene
9761238
rs1776180
EXO1
1.39
0.01
395 vs 411
455 vs 109
French
,
German
Mean age 101.3
G
C
Candidate Region/Gene
19698732
-
PARP1
—
1.0
239 vs 198
—
French
>100
—
—
Candidate Region/Gene
9587069
E2 / E3 / E4
APOE
—
1.2e-08
560 vs 560
—
French
centenarians 100th year or beyond, mean age 103.1
E4
—
Candidate Region/Gene
11280044
rs662
PON1
1.06
0.11
—
—
Danish
,
Dutch
,
French
,
German
,
Italian
,
Tatar
>/=80
—
—
Candidate Region/Gene
20362697
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9 of 34 variants
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