| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| ASP299GLY | TLR4 | — | 0.04 | 8 vs 8 | — | Italian | 25-50 | — | — | — | 16803999 |
| - | HRAS1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | 1 (specifically for SIRT3 in a French population) | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | SIRT3 | — | 0.145 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | TH | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | INS | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | IGF2 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4073591 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4073590 | DEAF1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs11040489 | KRTAP5-6 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4930001 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs800140 | TSPAN32 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs16928120 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | GSTM1 | — | 0.74 | 94 vs 418 | — | Italian | 100 years vs 46 years | — | — | - | 11162685 |
| rs2069762 | IL-2 | 1.43 | 0.096 | 168 vs 214 | — | Italian | Centenarians | G | T | Candidate Region/Gene | 16518704 |
| rs662 | PON1 | — | 1.0 | 579 vs 308 | — | Italian | Over 100 | G | A | Candidate Region/Gene | 12082503 |
| rs854560 | PON1 | — | 1.0 | 579 vs 308 | — | Italian | Over 100 | — | — | Candidate Region/Gene | 12082503 |
| codon 192 | PON1 | — | 1.0 | 192 vs 77 | — | Italian | 56 ages 66 to 89, 96 >90 | — | — | Candidate Region/Gene | 16799134 |
| codon 55 | PON1 | — | 1.0 | 192 vs 77 | — | Italian | 56 ages 66 to 89, 96 >90 | — | — | Candidate Region/Gene | 16799134 |
| Not specified | IL2 | — | 0.05 | 470 vs 120 | — | Italian, Bulgarian | Age range: 65-99 | — | — | Candidate Region/Gene | 21299522 |
| Not specified | IFNG | — | 0.05 | 707 vs 339 | — | Turkish, Polish, Italian, Bulgarian | Age range: 65-99 | — | — | Candidate Region/Gene | 21299522 |
| rs1800629 | TNF | — | 1.0 | 174 vs 224 | — | Italian | >100 | — | — | Candidate Region/Gene | 12676903 |
| rs1800629 | TNFa | — | 0.168 | See Description for details | — | Italian | Comparison 1: 66-91. Comparison 2: >88 | — | — | Candidate Region/Gene | 21865054 |
| rs361525 | TNFa | — | 0.156 | See Description for details | — | Italian | Comparison 1: 66-91. Comparison 2: >88 | — | — | Candidate Region/Gene | 21865054 |
| rs189037 | ATM | 1.45 | 0.12 | 128 vs 150 | — | Italian | Mean age 98.7 +/- 5.1 | — | — | Candidate Region/Gene | 22960875 |
| HP1/2 common polymorphism | HP | — | 0.05 | 200 (cases) vs 539 (initial) (initial) | — | Italian | >88 | — | — | Candidate Region/Gene | 21703254 |
