polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
ASP299GLY | TLR4 | — | 0.04 | 8 vs 8 | — | Italian | 25-50 | — | — | — | 16803999 |
rs884949 | ADARB2 | 1.19 | 0.0911 | 877 vs 1808 | Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538. | Northern European | 96–119 (median: 103) | AA | — | — | 20011587 |
rs2805533 | ADARB2 | 0.91 | 0.1904 | 877 vs 1808 | Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538. | Northern European | 96–119 (median: 103) | AA/AG | — | — | 20011587 |
rs2387653 | ADARB2 | 1.17 | 0.1053 | 877 vs 1808 | Southern Italian, age 90–109 (median 96): 459 vs 429. Ashkenazi Jewish, age 95–112 (median 100): 299 vs 269. Japanese, age 100-116 (median 106): 470 vs 538. | Northern European | 96–119 (median: 103) | AA | — | — | 20011587 |
GSTT1 gene deletion | GSTT1 | — | 0.001 | 447 | — | Danish | 77.4 | no deletion | deletion | - | 16574194 |
- | HRAS1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | 1 (specifically for SIRT3 in a French population) | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | SIRT3 | — | 0.145 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | TH | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | INS | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | IGF2 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4073591 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4073590 | DEAF1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs11040489 | KRTAP5-6 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4930001 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs800140 | TSPAN32 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs16928120 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
MTP -493G/T | MTP | — | 0.854 | — | — | Chinese | — | — | — | - | 23273182 |
- | GSTM1 | — | 0.74 | 94 vs 418 | — | Italian | 100 years vs 46 years | — | — | - | 11162685 |
rs4646903 | CYP1A1 | 1.03 | 0.23 | 205 vs 294 | — | German | 80-89; reference group: 17-79 | — | — | - | 15177664 |
rs1056836 | CYP1B1 | 0.63 | 0.78 | 205 vs 294 | — | German | 80-89; reference group: 17-79 | — | — | - | 15177664 |
rs1799814 | CYP1A1 | 1.16 | 1.0 | 205 vs 294 | — | German | 80-89; reference group: 17-79 | — | — | - | 15177664 |
R353Q | FVII | — | 0.61 | 113 vs 100 | — | Scottish | 96 years vs 32 years | — | — | - | 10744171 |
IVS7 | FVII | — | 0.69 | 113 vs 100 | — | Scottish | 96 vs 32 | — | — | - | 10744171 |
rs1800629 | TNF | — | 1.0 | 119 vs 118 | — | Jordanian | Mean age 90.2 | — | — | Candidate Region/Gene | 20518833 |
rs708272 | CETP | — | 1.0 | 12 vs 190 vs 105 | — | Greek | 99-111 | — | — | Candidate Region/Gene | 23389097 |